Tuesday 6 January 2015

Dyspepsia

Evidence Based Reports

Carbon-13 Urea Breath Test for Helicobacter Pylori Infection in Patients with Uninvestigated Ulcer-Like Dyspepsia: An Evidence-Based Analysis (2014)[HTA] NEW

Meta-analysis: helicobacter pylori 'test and treat' compared with empirical acid suppression for managing dyspepsia (2011)[DARE]

Chinese herbal medicine modified xiaoyao san for functional dyspepsia: meta-analysis of randomized controlled trials (2009)[DARE]

Clinical trial: a randomized trial of early endoscopy, Helicobacter pylori testing and empirical therapy for the management of dyspepsia in primary care (2009)[NHS EED]

Helicobacter pylori test and treat versus proton pump inhibitor in initial management of dyspepsia in primary care: multicentre randomised controlled trial (MRC-CUBE trial)(2009)[NHS EED]

Meta-analysis: Helicobacter pylori 'test and treat' compared with empirical acid suppression for managing dyspepsia (2008)[NHS EED]

Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia (2008)[DARE]

Cost-effectiveness analysis of two management strategies for dyspepsia (2008)[NHS EED]

Clinical Guidelines

Dyspepsia and gastro-oesophageal reflux disease (2014) [NICE] NEW

Dyspepsia - unidentified cause (2012)[CKS]

Dyspepsia - proven peptic ulcer (2012)[CKS]

Dyspepsia - proven non-ulcer (2012)[CKS]

Dyspepsia - proven gastro-oesophageal reflux disease (2012)[CKS]

Dyspepsia - pregnancy-associated (2012)[CKS]

Recent articles in core journals

Helicobacter pylori Eradication in Functional Dyspepsia: HEROES Trial. (2012) [EvidenceUpdates]

Efficacy of the 5-HT1A agonist tandospirone citrate in improving symptoms of patients with functional dyspepsia: a randomized controlled trial.(2009)[EvidenceUpdates]

Clinical trial: a randomized trial of early endoscopy, Helicobacter pylori testing and empirical therapy for the management of dyspepsia in primary care.(2009)[EvidenceUpdates]

Effect and cost-effectiveness of step-up versus step-down treatment with antacids, H2-receptor antagonists, and proton pump inhibitors in patients with new onset dyspepsia (DIAMOND study): a primary-care-based randomised controlled trial.(2009)[EvidenceUpdates]

Cost-effectiveness of and satisfaction with a Helicobacter pylori "test and treat" strategy compared with prompt endoscopy in young Asians with dyspepsia.(2008)[EvidenceUpdates]

Itopride in functional dyspepsia: results of two phase III multicentre, randomised, double-blind, placebo-controlled trials.(2008)[EvidenceUpdates]

Clinical trial: a randomized controlled cross-over study of flupenthixol + melitracen in functional dyspepsia.(2008)[EvidenceUpdates]

Helicobacter pylori test and treat versus proton pump inhibitor in initial management of dyspepsia in primary care: multicentre randomised controlled trial (MRC-CUBE trial).(2008)[BMJ]

eTextbooks

Dyspepsia (2014)[Mentor] updated

Clinical Queries

What drugs are considered first line for dyspepsia in a pregnant woman?(2008)[TRIPAnswers]

What investigations are recommended for children with dyspepsia? (2008)[TRIPAnswers]

What is the evidence for using regular gastroprotective proton pump inhibitors in patients having aspirin and diclofenac but with no symptoms of dyspepsia? (2008)[TRIPAnswers]

Patient Information

Indigestion (dyspepsia) in pregnancy (2014)[NHS Choice] updated

Indigestion (2014)[NHS Choice] updated

Indigestion (2014)[BUPA] updated

Indigestion medicines (2014)[BUPA] updated

Dyspepsia (Indigestion)(2014)[PatientUK] updated

Dyspepsia in Pregnancy (2014)[PatientUK]updated

Non-ulcer (Functional) Dyspepsia (2014)[PatientUK] updated


Important

1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at questions@attract.wales.nhs.uk or call 01495 332343.
2. If you would like to comment on this CME topic, or suggest a new topic for ATTRACTcme, go to the comments hyperlink below.

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