Monday, 19 January 2015

Helicobacter Pylori

Evidence Based Reports

Cost-effectiveness of the carbon-13 urea breath test for the detection of Helicobacter pylori: an economic analysis (2014)[NHS EED] NEW

Eradication of Helicobacter pylori for non-ulcer dyspepsia (2011) [Cochrane Library]

Eradication therapy for peptic ulcer disease in Helicobacter pylori positive patients. (2011) [Cochrane Library]

Helicobacter pylori eradication for Parkinson's disease. (2011)[Cochrane Library]

Usefulness of urea breath test for helicobacter pylori detection (2011)[HTA]

Eradication therapy for peptic ulcer disease in Helicobacter pylori positive patients (2011)[Cochrane Library]

Is there an increased risk of GERD after Helicobacter pylori eradication? A meta-analysis (2010)[DARE]

Empiric quadruple vs triple therapy for primary treatment of Helicobacter pylori infection: systematic review and meta-analysis of efficacy and tolerability (2010)[DARE]

Meta-analysis: four-drug, three-antibiotic, non-bismuth-containing "concomitant therapy" versus triple therapy for Helicobacter pylori eradication (2010)[DARE]

Helicobacter pylori infection (2009)[Clinical Evidence] subcription required

Sequential therapy or triple therapy for Helicobacter pylori infection: systematic review and meta-analysis of randomized controlled trials in adults and children (2009)[DARE]

Meta-analysis: Lactobacillus containing quadruple therapy versus standard triple first-line therapy for Helicobacter pylori eradication (2009)[DARE]

Moxifloxacin-based triple therapy versus clarithromycin-based triple therapy for first-line treatment of Helicobacter pylori infection: a meta-analysis of randomized controlled trials (2009)[DARE]

A systematic review of treating Helicobacter pylori infection with traditional Chinese medicine (2009)[DARE]

Effect of fermented milk-based probiotic preparations on Helicobacter pylori eradication: a systematic review and meta-analysis of randomized-controlled trials (2009)[DARE]

Adverse events with bismuth salts for Helicobacter pylori eradication: systematic review and meta-analysis (2008)[DARE]

Clinical Guidelines


Recent articles in core journals

Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial (2014)[EvidenceUpdates] NEW

Risk of recurrent Helicobacter pylori infection 1 year after initial eradication therapy in 7 Latin American communities. (2013) [JAMA]

Randomised clinical trial comparing sequential and concomitant therapies for Helicobacter pylori eradication in routine clinical practice. (2013) [EvidenceUpdates]

Optimized nonbismuth quadruple therapies cure most patients with Helicobacter pylori infection in populations with high rates of antibiotic resistance. (2013) [EvidenceUpdates]

Sequential versus triple therapy for the first-line treatment of Helicobacter pylori: a multicentre, open-label, randomised trial. (2013) [Lancet]

Helicobacter pylori eradication in functional dyspepsia: HEROES trial (2012) [EvidenceUpdates]

14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial.(2011)[Lancet]

Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. (2011)[Lancet]

Empirical levofloxacin-containing versus clarithromycin-containing sequential therapy for Helicobacter pylori eradication: a randomised trial.(2011)[EvidenceUpdates]

Comparison of the once-daily levofloxacin-containing triple therapy with the twice-daily standard triple therapy for first-line Helicobacter pylori eradication: a prospective randomised study. (2010)[EvidenceUpdates]

Levofloxacin-based and clarithromycin-based triple therapies as first-line and second-line treatments for Helicobacter pylori infection: a randomised comparative trial with crossover design. (2010)[EvidenceUpdates]

Association between helicobacter pylori and gastrointestinal symptoms in children. (2010)[EvidenceUpdates]

Empiric quadruple vs. triple therapy for primary treatment of Helicobacter pylori infection: Systematic review and meta-analysis of efficacy and tolerability. (2010)[EvidenceUpdates]

Sequential therapy or triple therapy for Helicobacter pylori infection: systematic review and meta-analysis of randomized controlled trials in adults and children. (2010)[EvidenceUpdates]

Meta-analysis: can Helicobacter pylori eradication treatment reduce the risk for gastric cancer? (2009)[Annals of Internal Medicine]

Meta-analysis: efficacy of bovine lactoferrin in Helicobacter pylori eradication. (2009)[EvidenceUpdates]

Duplicate breath testing to confirm eradication of Helicobacter pylori: incremental benefit and cost in 419 patients. (2009)[EvidenceUpdates]

eTextbooks

Helicobacter Pylori Infection (2014)[eMedicine] updated

Helicobacter Pylori (2014)[Mentor] updated

quadruple therapy for Helicobacter pylori eradication (2014)[GPnotebook] updated

Helicobacter pylori(2010)[GPnotebook]

Clinical Queries

Is there any evidence for treating helicobacter pylori in an otherwise well patient with no symptoms? (2012) [ATTRACT]

Is it possible to pass Helicobacter pylori person-to-person? (2009)[TRIPAnswers]

Is there a relation between H pylori infection and rosacea? Would H pylori eradication help management? (2009)[ATTRACT]

Patient Information

Helicobacter Pylori & Stomach Pain (2014)[PatientUK] updated

Helicobacter pylori (2009)[GPnotebook]

Important


1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at questions@attract.wales.nhs.uk or call 01495 332343.
2. If you would like to comment on this CME topic, or suggest a new topic for ATTRACTcme, go to the comments hyperlink below.