Evidence Based Reports
Statins for women with polycystic ovary syndrome not actively trying to conceive (2011)[Cochrane] NEW
Statins for multiple sclerosis (2011) [Cochrane] NEW
Statins for the primary prevention of cardiovascular disease (2011)[Cochrane] NEW
Statins for the treatment of dementia (2010)[Cochrane][Cochrane PEARLS]
Statins for children with familial hypercholesterolemia (2010)[Cochrane]
Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 randomized controlled trials involving 65229 participants (2010)[DARE]
Effect of statins pretreatment on periprocedural myocardial infarction in patients undergoing percutaneous coronary intervention: a meta-analysis (2010)[DARE]
Differing effect of statins on insulin sensitivity in non-diabetics: a systematic review and meta-analysis (2010)[DARE]
HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis (2009)[Cochrane]
HMG CoA reductase inhibitors (statins) for kidney transplant recipients (2009)[Cochrane]
Statins for age-related macular degeneration (2009) [Cochrane]
Statins for the prevention of dementia (2009)[Cochrane]
Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review (2009)[DARE]
Statin therapy and risk of developing type 2 diabetes: a meta-analysis (2009) [DARE]
Statins for the prevention and treatment of infections: a systematic review and meta-analysis (2009)[DARE]
The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials (2009)[DARE]
Statins for secondary prevention in elderly patients: a hierarchical Bayesian meta-analysis (2008)[DARE]
Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trials (2008)[DARE]
The efficacy and safety of intensive statin therapy: a meta-analysis of randomized trials (2008)[DARE]
Statins and cancer: a meta-analysis of case-control studies (2008)[DARE]
Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients (2008)[DARE]
Impact of preoperative statin therapy on adverse postoperative outcomes in patients undergoing cardiac surgery: a meta-analysis of over 30 000 patients (2008)[DARE]
Statins for infection and sepsis: a systematic review of the clinical evidence (2008)[DARE]
Statin use and development of atrial fibrillation: a systematic review and meta-analysis of randomized clinical trials and observational studies (2008)[DARE]
Clinical Guidelines
Lipid modification - primary and secondary CVD prevention (2008)[CKS]
Lipid modification (2008)[NICE]
Recent articles in core journals
Effect of two intensive statin regimens on progression of coronary disease (2011) [NEJM] NEW
Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. (2011) [NEJM] NEW
Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis. (2011)[JAMA] NEW
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials (2010)[Lancet]
Meta-analysis: Statin Therapy Does Not Alter the Association Between Low Levels of High-Density Lipoprotein Cholesterol and Increased Cardiovascular Risk (2010)[Annals of Internal Medicine]
Statin use and the prevention of venous thromboembolism: a meta-analysis (2010)[Int J Clin Pract]
eTextbooks
Statins (2010)[GP Notebook]
Clinical Queries
Which statin is safest in renal failure? (2011) [TRIPanswers] NEW
Do statins cause amnesia? (2010) [NELM]
Do statins cause alopecia? (2010) [NELM]
Should patients on statins take Coenzyme Q10 supplementation to reduce the risk of myotoxicity? (2010) [NELM]
What is the current guidance on statin treatment for primary prevention in patients with calculated 10-yr CVD risk < 20% but Total cholesterol/HDL ratio > 6.0? (2010)[ATTRACT]
Patient Information
Statins and Other Lipid Lowering Drugs (2011)[Patient UK] Updated
Cholesterol-lowering medicines, statins (2010)[NHS Choices]
Important
1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at questions@attract.wales.nhs.uk or call 01495 332343.
2. If you would like to comment on this CME topic, or suggest a new topic for ATTRACTcme, go to the comments hyperlink below.
Statins for women with polycystic ovary syndrome not actively trying to conceive (2011)[Cochrane] NEW
Statins for multiple sclerosis (2011) [Cochrane] NEW
Statins for the primary prevention of cardiovascular disease (2011)[Cochrane] NEW
Statins for the treatment of dementia (2010)[Cochrane][Cochrane PEARLS]
Statins for children with familial hypercholesterolemia (2010)[Cochrane]
Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 randomized controlled trials involving 65229 participants (2010)[DARE]
Effect of statins pretreatment on periprocedural myocardial infarction in patients undergoing percutaneous coronary intervention: a meta-analysis (2010)[DARE]
Differing effect of statins on insulin sensitivity in non-diabetics: a systematic review and meta-analysis (2010)[DARE]
HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis (2009)[Cochrane]
HMG CoA reductase inhibitors (statins) for kidney transplant recipients (2009)[Cochrane]
Statins for age-related macular degeneration (2009) [Cochrane]
Statins for the prevention of dementia (2009)[Cochrane]
Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review (2009)[DARE]
Statin therapy and risk of developing type 2 diabetes: a meta-analysis (2009) [DARE]
Statins for the prevention and treatment of infections: a systematic review and meta-analysis (2009)[DARE]
The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials (2009)[DARE]
Statins for secondary prevention in elderly patients: a hierarchical Bayesian meta-analysis (2008)[DARE]
Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trials (2008)[DARE]
The efficacy and safety of intensive statin therapy: a meta-analysis of randomized trials (2008)[DARE]
Statins and cancer: a meta-analysis of case-control studies (2008)[DARE]
Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients (2008)[DARE]
Impact of preoperative statin therapy on adverse postoperative outcomes in patients undergoing cardiac surgery: a meta-analysis of over 30 000 patients (2008)[DARE]
Statins for infection and sepsis: a systematic review of the clinical evidence (2008)[DARE]
Statin use and development of atrial fibrillation: a systematic review and meta-analysis of randomized clinical trials and observational studies (2008)[DARE]
Clinical Guidelines
Lipid modification - primary and secondary CVD prevention (2008)[CKS]
Lipid modification (2008)[NICE]
Recent articles in core journals
Effect of two intensive statin regimens on progression of coronary disease (2011) [NEJM] NEW
Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. (2011) [NEJM] NEW
Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis. (2011)[JAMA] NEW
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials (2010)[Lancet]
Meta-analysis: Statin Therapy Does Not Alter the Association Between Low Levels of High-Density Lipoprotein Cholesterol and Increased Cardiovascular Risk (2010)[Annals of Internal Medicine]
Statin use and the prevention of venous thromboembolism: a meta-analysis (2010)[Int J Clin Pract]
eTextbooks
Statins (2010)[GP Notebook]
Clinical Queries
Which statin is safest in renal failure? (2011) [TRIPanswers] NEW
Do statins cause amnesia? (2010) [NELM]
Do statins cause alopecia? (2010) [NELM]
Should patients on statins take Coenzyme Q10 supplementation to reduce the risk of myotoxicity? (2010) [NELM]
What is the current guidance on statin treatment for primary prevention in patients with calculated 10-yr CVD risk < 20% but Total cholesterol/HDL ratio > 6.0? (2010)[ATTRACT]
Patient Information
Statins and Other Lipid Lowering Drugs (2011)[Patient UK] Updated
Cholesterol-lowering medicines, statins (2010)[NHS Choices]
Important
1. If you are a Welsh Primary Care Professional with a clinical query send it to ATTRACT online or email us at questions@attract.wales.nhs.uk or call 01495 332343.
2. If you would like to comment on this CME topic, or suggest a new topic for ATTRACTcme, go to the comments hyperlink below.
